Contents
VII Foreword
Savage, M.O. (London)
IX Preface
Delemarre-van de Waal, H.A. (Amsterdam)
1 Secular Trend of Timing of Puberty
Delemarre-van de Waal, H.A. (Amsterdam)
15 Fetal Nutrition and Timing of Puberty
van Weissenbruch, M.M.; Engelbregt, M.J.T.; Veening, M.A.;
Delemarre-van de Waal, H.A. (Amsterdam)
34 Adrenal Function of Low-Birthweight Children
Ong, K. (Cambridge)
54 Puberty and Fertility in Congenital Adrenal Hyperplasia
Otten, B.J.; Stikkelbroeck, M.M.L.; Claahsen-van der Grinten, H.L.;
Hermus, A.R.M.M. (Nijmegen)
67 Molecular Genetics of Isolated Hypogonadotropic Hypogonadism
and Kallmann Syndrome
Karges, B. (Ulm); de Roux, N. (Paris)
81 Hypothalamic Hamartoma: A Paradigm/Model for Studying
the Onset of Puberty
Jung, H.; Parent, A.-S.; Ojeda, S.R. (Beaverton, Oreg.)
94 Gonadotropin-Releasing Hormone Analogue Treatment for Precocious
Puberty. Twenty Years of Experience
Heger, S.; Sippell, W.G. (Kiel); Partsch, C.-J. (Esslingen)
126 Very Long-Term Follow-Up of Girls with Early and Late Menarche
Johansson, T.; Ritzén, E.M. (Örebro)
137 Polycystic Ovary Syndrome in Adolescence.
New Insights in Pathophysiology and Treatment
Homburg, R. (Amsterdam)
150 Reversing Sex Steroid Deficiency and Optimizing Skeletal Development
in the Adolescent with Gonadal Failure
Vanderschueren, D.; Vandenput, L.; Boonen, S. (Leuven)
166 Present and Future Options for the Preservation of Fertility in
Female Adolescents with Cancer
Beerendonk, C.C.M.; Braat, D.D.M. (Nijmegen)
176 Author Index
177 Subject Index
