List of Contributors . . . . . . . . . . . . . . . . . .vii
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
P I E ………… 1
1. Obesity as a Global Problem ……. 3
Vicki J. Antipatis and Tim P. Gill
2. The Epidemiology of Obesity . . . . . . 23
Jacob C. Seidell
3. Body Weight, Body Composition
and Longevity . . . . . . . . . . . . . . . . . . 31
David B. Allison, Moonseong Heo,
Kevin R. Fontaine and
Daniel J. Hoffman
P II D . . . . . . . . . . . . . . 49
4. Anthropometric Indices of Obesity and
Regional Distribution of Fat Depots . 51
T.S. Han and M.E.J. Lean
5. Screening the Population . . . . . . . . . . 67
Bernt Lindahl
6. Evaluation of Human Adiposity . . . . 85
Steven B. Heymsfield, Daniel J.
Hoffman, Corrado Testolin and
ZiMian Wang
P III A R
O P . . . . 99
7. Role of Neuropeptides and Leptin
in Food Intake and Obesity . . . . . . . 101
Bernard Jeanrenaud and
Franc ̧oise Rohner-Jeanrenaud
8. Regulation of Appetite and the
Management of Obesity . . . . . . . . . 113
John E. Blundell
9. Physiological Regulation of
Macronutrient Balance . . . . . . . . . . 125
Susan A. Jebb and Andrew M.
Prentice
10. Fat in the Diet and Obesity . . . . . . . 137
Berit Lilienthal Heitmann and
Lauren Lissner
11. Energy Expenditure at Rest and
During Exercise . . . . . . . . . . . . . . . 145
Bjo ̈ rn Ekblom
12. Exercise and Macronutrient
Balance . . . . . . . . . . . . . . . . . . . . . 155
Angelo Tremblay and
Jean-Pierre Despre ́ s
P IV P T
O . . . . . . . . . . . . 163
13. The Specificity of Adipose Depots . . 165
Caroline M. Pond
14. Causes of Obesity and
Consequences of Obesity Prevention
in Non-human Primates and Other
Animal Models . . . . . . . . . . . . . . . . 181
Barbara C. Hansen
15. Social Status, Social Stress and Fat
Distribution in Primates . . . . . . . . . 203
Carol A. Shively and Jeanne M.
Wallace
16. Centralization of Body Fat . . . . . . . 213
Per Bjo ̈ rntorp
International Textbook of Obesity. Edited by Per Bjorntorp.
Copyright © 2001 John Wiley & Sons Ltd
Print ISBNs: 0-471-988707 (Hardback); 0-470-846739 (Electronic)
17. Obesity and Hormonal
Abnormalities . . . . . . . . . . . . . . . . . 225
Renato Pasquali and Valentina
Vicennati
18. Cortisol Metabolism . . . . . . . . . . . . 241
Brian R. Walker and Jonathan
R. Seckl
19. Drug-induced Obesity . . . . . . . . . . . 269
Leif Breum and Madelyn H.
Fernstrom
20. Pregnancy . . . . . . . . . . . . . . . . . . . 283
Helen E. Harris
21. Social and Cultural Influences on
Obesity . . . . . . . . . . . . . . . . . . . . . 305
Jeffery Sobal
22. Cessation of Smoking and Body
Weight . . . . . . . . . . . . . . . . . . . . . . 323
Kenneth D. Ward, Robert C. Klesges
and Mark W. Vander Weg
P V C . . . . . . . . . 337
23. Visceral Obesity and the Metabolic
Syndrome . . . . . . . . . . . . . . . . . . . . 339
Roland Rosmond
24. Obesity and Type 2 Diabetes
Mellitus . . . . . . . . . . . . . . . . . . . . . 351
Allison M. Hodge, Maximilian P. de
Courten and Paul Zimmet
25. Cardiovascular Disease . . . . . . . . . . 365
Antonio Tiengo and Angelo Avogaro
26. Obesity, Overweight and Human
Cancer . . . . . . . . . . . . . . . . . . . . . . 379
Michael Hill
27. Pulmonary Diseases (Including Sleep
Apnoea and Pickwickian Syndrome) 385
Tracey D. Robinson and Ronald
R. Grunstein
28. Obesity and Gallstones . . . . . . . . . . 399
S. Heshka and S. Heymsfield
P VI M . . . . . . . . . 411
29. Health Benefits and Risks of Weight
Loss . . . . . . . . . . . . . . . . . . . . . . . . 413
Lalita Khaodhiar and George L.
Blackburn
30. Treatment: Diet . . . . . . . . . . . . . . . 441
Stephan Ro ̈ ssner
31. Recent and Future Drugs for the
Treatment of Obesity . . . . . . . . . . . 451
Luc F. van Gaal, Ilse L. Mertens
and Ivo H. De Leeuw
32. Treatment: Hormones . . . . . . . . . . . 471
Bjo ̈ rn Andersson, Gudmundur
Johannsson and Bengt-A ke Bengtsson
33. Why Quality of Life Measures Should
Be Used in the Treatment of Patients
with Obesity . . . . . . . . . . . . . . . . . . 485
Marianne Sullivan, Jan Karlsson,
Lars Sjo ̈ stro ̈ m and Charles Taft
34. Surgical Treatment of Obesity . . . . 511
John G. Kral
35. Swedish Obese Subjects, SOS . . . . . 519
Lars Sjo ̈ stro ̈ m
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . 535
