Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix
Foreword by Professor W.I. McDonald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
CHAPTER 1: Terminology and Disease Description. . . . . . . . . . . . . . . . . . 1
CHAPTER 2: The Framing of Multiple Sclerosis. . . . . . . . . . . . . . . . . . . . 13
CHAPTER 3: The Palsy without a Name: Suffering
with Paraplegia 1395–1868 . . . . . . . . . . . . . . . . . . . . . . . . . . 19
CHAPTER 4: The Steps Toward a Discovery:
The Early Medical Reports . . . . . . . . . . . . . . . . . . . . . . . . . . 61
CHAPTER 5: The Building Blocks of a Discovery. . . . . . . . . . . . . . . . . . . 95
CHAPTER 6: The Contribution of J.M. Charcot—1868 . . . . . . . . . . . . . 103
CHAPTER 7: The Medical Reports After Charcot . . . . . . . . . . . . . . . . . 139
CHAPTER 8: Clarifying the Pathology: James Dawson . . . . . . . . . . . . . 189
CHAPTER 9: The Journal of a Disappointed Man . . . . . . . . . . . . . . . . . 195
CHAPTER 10: Experimentation, Meetings, Reviews,
and Symposia, 1920–1960. . . . . . . . . . . . . . . . . . . . . . . . . . 203
CHAPTER 11: Searching for a Cause of MS . . . . . . . . . . . . . . . . . . . . . . . 229
CHAPTER 12: Classifying and Measuring MS . . . . . . . . . . . . . . . . . . . . 319
CHAPTER 13: The Nature of the MS Plaque. . . . . . . . . . . . . . . . . . . . . . 337
CHAPTER 14: Investigations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
CHAPTER 15: Searching for Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391
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CHAPTER 16: Multiple Sclerosis and the Public: Societies,
Narratives, and the Media . . . . . . . . . . . . . . . . . . . . . . . . . 505
Afterword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529
A Chronology of Events in the History of MS . . . . . . . . . . . . . . . . . . . . 535
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 549