CHLORTHALIDONE
Jeff M. Singer, Michael J. O’Hare,
Carl R. Rehrn, and John E. Zarembo
Revlon Heulth Care Group
Tuckuhoe, New York
Introduction
1. Description
1.1
1.2 Trade Names
1.3 Appearance, Color
2. Physical Properties
2.1 Spectra
2.2 Physical Properties of the Solid
2.3 Solubility
2.4 Ionization Constant (pKa)
Name, Formula, Molecular Weight, Chemical Names
3. Synthesis
4. Stability
5. Chemical Properties
5.1 Identity Tests
5.2 Methods of Analysis
S.3 Chromatographic Analysis
6. Determination in Biological Fluids
7. Bioavailability and Pharmacokinetics
References